Table of Contents
Credits
Host: Sara Dong
Guests: Daniel Minter, Sarah Doernberg
Content is based on the CID article featured in this episode although with additional writing by Sara Dong
Audio Editing: Bentley Brown
Content editing and production by Sara Dong with support from the Infectious Diseases Society of America (IDSA)
Our Guests
Daniel Minter, MD
Dr. Dan Minter is an infectious diseases physician at UCSF (having trained there for medical school, residency, and fellowship). He cares for patients with a broad range of bacterial, fungal, viral, and parasitic infections. He has a special interest in caring for immunocompromised patients as well as patients with neurologic infections. His primary academic interests involve medical education and clinical reasoning. He is involved in teaching medical students, residents, and fellows in a variety of settings.
Sarah Doernberg, MD, MAS
Dr. Sarah Doernberg is a Professor in the Division of Infectious Diseases and the Medical Director of Adult Antimicrobial Stewardship at UCSF Medical Center. She has an active outpatient Infectious Diseases Clinic and sees inpatients on the Transplant Infectious Diseases service. Her clinical research focuses on diagnosis and treatment of antibiotic resistant infections and antimicrobial stewardship. She received her BA from Harvard University in Biology with a focus in Neurobiology and received her MD from Yale University School of Medicine. She completed her Internal Medicine residency and Infectious Diseases fellowship at UCSF. She also received a Masters’ degree in advanced studies through the Training in Clinical Research Program at UCSF.
Culture
Daniel shared his plans to hopefully get a dog soon
Sarah spends a lot of time watching her children play sports and is also excited that the Bay Area is getting a National Women’s Soccer League team
Consult Notes
Welcome to this Febrile StAR episode!
These StAR episodes feature discussions with authors from State-of-the-Art Review articles from the Clinical Infectious Diseases journal (CID).
This episode is based on: Minter DJ, Appa A, Chambers HF, Doernberg SB. Contemporary Management of Staphylococcus aureus Bacteremia-Controversies in Clinical Practice. Clin Infect Dis. 2023 Nov 30;77(11):e57-e68. doi: 10.1093/cid/ciad500. PMID: 37950887.
Journal companion article – Executive summary link: https://academic.oup.com/cid/article/77/11/1489/7453594
Infographics
Goal
Listeners will be able to discuss contemporary management and noted controversies in management of Staphylococcus aureus bacteremia
Learning Objectives
After listening to this episode, listeners will be able to:
- Discuss situations in which transesophageal echocardiography should be pursued for Staph aureus bacteremia
- Compare cefazolin vs. anti-staphylococcal penicillins as definitive treatment for MSSA infection
- Describe agents available for definitive treatment of MRSA infection
Disclosures
Febrile podcast reports no relevant financial disclosures
Potential conflicts of interest are noted in the CID article as well as reproduced below:
DJM: reports payment from the Antimicrobial Resistance Leadership Group for participation in a systematic review and travel support from the University of California, San Francisco (UCSF), ID Division to attend IDWeek.
SBD: reports funding for clinical research studies from Gilead, Pfizer, F2G, Regeneron, Chan Zuckerberg Biohub, and NIH/NIAID; personal consulting fees from Genentech and Janssen/J+J; travel support from IDSA to speak at IDWeek; a patent for Mif agonists and antagonist and therapeutic uses (US20100143379A1); roles on the IDSA Antibacterial Resistance Committee, CADPH HAI Advisory Committee, Antibacterial Resistance Leadership Group Innovations Group, Laboratory Center, Mentorship Committee, Gram Positive Committee, and Immunosuppressed Host Group; and compensation for clinical events committee participation from Shinogi, Basilea, and Duke Clinical Research Institute
Other potential conflicts of interest from authors that were not on the podcast recording.
HFC reports an institutional grant from the National Institutes of Health/National Institute on Allergy and Infectious Diseases (NIH/NIAID) for the Antibacterial Resistance Leadership Group (UM1AI104681); royalties earned as editor for The Sanford Guide to Antimicrobial Therapy; payment for expert testimony in a patent dispute for Nexus Pharmaceuticals and a product liability case for Eli Lilly; support from Merck for participation in a Data and Safety Monitoring or Advisory Board; and stock in Moderna and Merck (spouse’s IRA).
AA reports no potential conflicts
Citation
Minter, D., Doernberg, S., Dong, S. “#106: StAR: Staph aureus bacteremia”. Febrile: A Cultured Podcast. https://player.captivate.fm/episode/41e7a78f-6d64-4140-8633-42bbef405e32/