Table of Contents
Credits
Hosts: Sara Dong
Guests: Chelsea Gorsline, Courtney Harris, Rebecca Kumar
This episode is structured off of the publication “They paged me what?: A transplant infectious disease guide to donor calls.” with additional writing by Sara Dong
Edited and Produced by Sara Dong with support from the Infectious Diseases Society of America (IDSA)
Our Guests
Chelsea Gorsline, MD
Dr. Chelsea Gorsline is a Transplant ID physician and assistant professor at The University of Kansas Medical Center in Kansas City, KS. She completed her internal medicine residency, general and transplant ID fellowship training at Vanderbilt University Medical Center in Nashville, TN. At KUMC, she is the medical director of Immunocompromised Antimicrobial Stewardship, the director of the Transplant ID Pathway for the ID fellowship and the director of the FitzSimmons Summer ID Research Fellowship for medical students.
Courtney Harris, MD
Dr. Courtney Harris is a Transplant ID physician and assistant professor at The Medical University of South Carolina in Charleston, SC. She completed her residency and chief residency at Mayo Clinic in Minnesota, general and transplant ID fellowship at the Harvard combined program of Brigham and Women’s Hospital and Mass General in Boston. At MUSC, she is the director of the transplant ID fellowship program, director of cardiac transplant ID, and director of the medical student elective/selective in ID.
Rebecca Kumar, MD
Dr. Rebecca Kumar is a Transplant ID physician and assistant professor at MedStar Georgetown University Hospital in the Division of Infectious Diseases and Tropical Medicine. She previously completed her internal medicine residency at Medstar Georgetown University Hospital in Washington DC followed by fellowship in infectious diseases at Northwestern University in Chicago.
Culture
Chelsea: the band Fontaines DC, TV show Severance
Courtney: fantasy novel series Throne of Glass
Rebecca: TV show The White Lotus
Consult Notes
Consult Q
We went through four example donor call consult questions!
This episode was structured around this publication:
Check out Figure 1 and Table 1 below
Here are a few additional resources related to the topics discussed:
- Two papers related to transmission of West Nile Virus in organ transplantation:
- An investigation of a cluster of patients with WNV transmission via organ transplantation: Iwamoto M, Jernigan DB, Guasch A, et al. Transmission of West Nile virus from an organ donor to four transplant recipients. N Engl J Med. 2003;348(22):2196-2203. doi:10.1056/NEJMoa022987
- A description of WNV SOT transmission and considerations for donor screening practices: Soto RA, McDonald E, Annambhotla P, et al. West Nile Virus Transmission by Solid Organ Transplantation and Considerations for Organ Donor Screening Practices, United States. Emerg Infect Dis. 2022;28(2):403-406. doi:10.3201/eid2802.211697
- Some references related to Strongyloides screening in transplant:
- Ruth Adekunle, Deeksha Jandhyala, Jessica Lewis, 1383. Universal Strongyloides Screening in a Heart Transplant Program in South Carolina: Just How Endemic Is It?, Open Forum Infectious Diseases, Volume 8, Issue Supplement_1, November 2021, Page S777, https://doi.org/10.1093/ofid/ofab466.1575
- Kim JH, Kim DS, Yoon YK, Sohn JW, Kim MJ. Donor-derived strongyloidiasis infection in solid organ transplant recipients: a review and pooled analysis. Transplant Proc. 2016;48:2442-2449.15. Buonfrate D, Salas-Coronas J, Muñoz J, et al.
- Buonfrate D, Salas-Coronas J, Muñoz J, et al. Multiple-dose versus single-dose ivermectin for Strongyloides stercoralis infection (Strong Treat 1 to 4): a multicentre, open-label, phase 3, randomised controlled superiority trial. Lancet Infect Dis. 2019;19(11):1181-1190. doi:10.1016/S1473-3099(19)30289-0
- Camargo JF, Simkins J, Anjan S, et al. Implementation of a Strongyloides screening strategy in solid organ transplant donors and recipients. Clin Transplant. 2019;33(4):e13497. doi:10.1111/ctr.13497
Our guests shared the Transplant ID Early Career Network
- You can follow TxID ECN on BlueSky
- TID publications:
- Social Media Savvy, It’s More Than Just the #Hashtags: How the Use of Social Media in Transplant Infectious Diseases Can Impact the Field and Patients
- Road map to success: Advice for transplant infectious diseases job interviews, negotiation, and early career development
- The pre-transplant evaluation: Considerations for trainees and early career transplant infectious diseases clinician
- Not Just an Oxymoron: The Utilitarian’s Guide to Antimicrobial Stewardship in Transplant Infectious Diseases
- Beginners guide to protocol writing in transplant infectious diseases
- The nuts and bolts of transplant infectious disease training
- “They paged me what?”: A transplant infectious disease guide to donor calls
Infographics
Goal
Listeners will be able to describe and apply a systematic approach to donor call
Learning Objectives
After listening to this episode, listeners will be able to:
- Define donor call in transplant infectious diseases
- Describe the considerations for accepting donors with known or suspected infection
- Identify that an organ from a donor with encephalopathy of unknown etiology should not be accepted
Disclosures
Febrile podcast and host report no relevant financial disclosures
Courtney E. Harris: Dynamed (Advisory Board)
Chelsea A. Gorsline: F2G Ltd (Clinical Trial Funding)
Rebecca N. Kumar: AstraZeneca (Speakers Bureau) and Regeneron (Research Grant)
Citation
Gorsline, C., Harris, C., Kumar, R., Dong, S. “#117: They Paged Me What? A TID Guide to Donor Call”. Febrile: A Cultured Podcast. https://player.captivate.fm/episode/a203bb01-39be-4a0a-8ca7-cd69ee71927b/