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Febrile #122: StAR: Protect the Macrolide! NTM Pulmonary Disease

122 Cover Art OPT

Summary

This StAR episode features the CID State-of-the-Art Review on  Nontuberculous Mycobacterial Pulmonary Disease: Patients, Principles, and Prospects.

Table of Contents

Credits

Host: Sara Dong

Guests: Minh-Vu Nguyen, Charles Daley, Reeti Khare

Content is based on the CID article featured in this episode although with additional writing by Sara Dong

Produced by Sara Dong with support from the Infectious Diseases Society of America (IDSA)

Our Guests

Minh-Vu Nguyen, MD, MSc

Minh-Vu, or simply Vu, is a recent former Mycobacterial Research Fellow at National Jewish Health. He is now a new Assistant Professor of Medicine in the Division of Infectious Diseases at UC Davis Health in Sacramento, CA, where he and his Pulmonary colleagues have started building a multidisciplinary NTM Care Center.

Reeti Khare, PhD

Reeti is an Associate Professor and Infectious Disease Laboratory Director at National Jewish Health.

Charles Daley, MD, ATSF, FCCP

Chuck is a Professor of Medicine at National Jewish Health, University of Colorado, and Icahn School of Medicine at Mt. Sinai. He is Chief of the Division of Mycobacterial and Respiratory Infections at National Jewish Health and Chief Research Officer at the new Bronchiectasis and NTM Association.

Culture

Reeti shared her love for anything chocolate

Vu had recently adopted two adolescent cats

Chuck shared the classic movie, Forrest Gump

Consult Notes

Welcome to this Febrile StAR episode!

These StAR episodes feature discussions with authors from State-of-the-Art Review articles from the Clinical Infectious Diseases journal (CID).

This episode is based on: Nguyen MH, Haas MK, Kasperbauer SH, et al. Nontuberculous Mycobacterial Pulmonary Disease: Patients, Principles, and Prospects. Clin Infect Dis. 2024;79(4):e27-e47. doi:10.1093/cid/ciae421

Journal companion article – Executive summary link: https://academic.oup.com/cid/article-abstract/79/4/805/7823163

Goal

Listeners will be able to describe key principles in the care of patients with nontuberculous mycobacterial pulmonary disease (NTM-PD).

Learning Objectives

After listening to this episode, listeners will be able to:

  • Describe the clinical presentation and diagnosis of NTM-PD
  • Summarize a general treatment framework for NTM-PD

Disclosures

Febrile podcast reports no relevant financial disclosures

Potential conflicts of interest are noted in the CID article as well as reproduced below:

  • Guests on podcast:
    • Nguyen MH: Supported by the National Jewish Health Lowerre Mycobacterial Research Fellowship
    • Daley CL: grant support from AN2 Therapeutics, Bugworks, Insmed, Juvabis, and Paratek Pharmaceuticals; advisory board work with AN2 Therapeutics, AstraZeneca, Cepheid, Hyfe, Insmed, MannKind, Matinas Biopharma, NobHill, Spero Therapeutics, and Zambon; consulting with Genentech and Pfizer; and data monitoring committee work with Otsuka Pharmaceutical and the Gates Foundation.
  • Co-authors (not on podcast):
    • Kasperbauer SH: consulting with AN2 Therapeutics, Insmed, and Paratek Pharmaceuticals; investigator work with Insmed; and speaker work with AN2 Therapeutics, Insmed, and Paratek Pharmaceuticals
    • Mitchell JD: consulting with Intuitive Surgical
    • Griffith DE: advisory board work with Insmed and consulting with AN2 Therapeutics, Insmed, and Paratek Pharmaceuticals

Citation

Nguyen MVH, Khare R, Daley CL, Dong, SW. “#122: StAR: Protect the Macrolide! NTM Pulmonary Disease ”. Febrile: A Cultured Podcast. https://player.captivate.fm/episode/ad8104ea-cf23-40b6-8a82-01130264d213/

Transcript

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